Feature |
GSK3β plays an essential role in Ras degradation and that inhibition of this degradation pathway by aberrant Wnt/β-catenin signaling may contribute to Ras-induced transformation in colorectal tumorige |
Application |
WB,IP,IHC |
Species |
Homo sapiens |
Targets |
H-Ras |
Catergory |
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Title |
Ras stabilization through aberrant activation of Wnt/β-catenin signaling promotes intestinal tumorigenesis. |
Publication |
Jeong WJ, Sci Signal, 2012 |
Methods |
Phospho-T144/T148 H-Ras polyclonal antibodies were generated by immunizing rabbits with a keyhole limpet hemocyanin (KLH) carrier protein–conjugated phosphorylated peptide (residues 140 to 152; PYIEpTSAKpTRQGV; Abmart Inc.). |
Figures |
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Highlights |
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