| Feature |
CGG repeat expansion in the 5'UTR of FMR1 is thought to elicit toxicity as RNA. |
| Application |
WB, IHC |
| Species |
Mus musculus |
| Targets |
FMR1 |
| Catergory |
RNA binding |
| Title |
CGG repeat-associated translation mediates neurodegeneration in fragile X tremor ataxia syndrome. |
| Publication |
Henry L. Paulson, Neuron, 2013 |
| Methods |
Monoclonal mouse antibodies 2J7 and 2C13 were developed commercially (Abmart) against a 10 amino acid peptide, LAGLKRRWRS, in the predicted carboxyl terminus of the FMR1polyG. |
| Figures |
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| Highlights |
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