| Feature | L1 RNP is linked by a both protein-protein (PCNA) and protein-RNA (UPF1) interactions; PCNA binds to ORF2p via a PIP box and is critical for retrotransposition. |
| Application | WB |
| Species | Homo sapiens |
| Targets | ORF1 |
| Catergory | RNA binding |
| Title | Affinity proteomics reveals human host factors implicated in discrete stages of LINE-1 retrotransposition. |
| Publication | Taylor MS, Cell, 2013 |
| Methods | Mouse monoclonal anti-human L1 ORF1 clone 4H1 was purchased from ABmart. |
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| Highlights |
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