Feature |
Impaired granulocyte PKA function in AERD may lead to dysregulated control of 5-lipoxygenase activity by prostaglandin E2. |
Application |
FACS |
Species |
Homo sapiens |
Targets |
EP2R(E prostanoid2) |
Catergory |
GPCR |
Title |
Prostaglandin E2 resistance in granulocytes from patients with aspirin-exacerbated respiratory disease |
Publication |
Laidlaw TM, J Allergy Clin Immunol, 2014 |
Methods |
EP2 receptor expression was analyzed on permeabilized whole blood by using a mouse anti-human monoclonal antibody directed against a fusion peptide based on extracellular portions of the human EP2 receptor (Abmart,Shanghai, China) |
Figures |
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