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  • Feature Monoclonal antibodies block the interaction and abolish IL1β cell signalling.
    Application WB, Functional
    Species Mus musculus
    Targets IL1RAcP
    Catergory Membrane receptor
    Title Protein painting reveals solvent-excluded drug targets hidden within native protein-protein interfaces.
    Publication Alessandra Luchini, Nat Commun, 2014
    Methods Mouse IgG mAbs (Abmart) were raised against the functionally active portion of IL1RAcPArg286 peptide (TINESISHSRTEDETRTQILS).