| Feature | Monoclonal antibodies block the interaction and abolish IL1β cell signalling. |
| Application | WB, Functional |
| Species | Mus musculus |
| Targets | IL1RAcP |
| Catergory | Membrane receptor |
| Title | Protein painting reveals solvent-excluded drug targets hidden within native protein-protein interfaces. |
| Publication | Alessandra Luchini, Nat Commun, 2014 |
| Methods | Mouse IgG mAbs (Abmart) were raised against the functionally active portion of IL1RAcPArg286 peptide (TINESISHSRTEDETRTQILS). |
| Figures |
)
|
| Highlights |
UrgentMab™: Thinking is cheap. Test your ideas, fast and furious. |
 |
|
Custom monoclonal antibody in one month. As low as $200-300 per antigen. |
|
A product of Absolution |
|
SEAL™: Today's out-of-reach protein targets made accessible. |
|
|
Same budget, 5-10 times more antibodying SEAL your protein. Successes too. |
|
A product of Absolution |
|
PETAL™: Fast and high throughput antibody discover platform. |
 |
|
Deliver customized antibody in two weeks at price of category antibody Proteome-scale antibody discovery for any organism or proteome Biomarker discovery for biological processes or human diseases |
|
A product of Absolution |
|
AbFocus™: Target all the modification sites of your protein, affordably. |
|
|
Test them with a panel of AbFocus antibodies It is so affordable that you can focus on testing, not guessing |
|
A product of Absolution |
Mabome™: Catch the antibody gold rush.? Lead the next omics revolution. |
|
|
First-ever antibody proteomics technology. High quality monoclonal antibodies for your favorite proteome. As low as $19/monoclonal antibody |
|
A product of Absolution |
AbTarget™: Performing antibody for your proteome.? Guaranteed |
|
|
Fast, efficient monoclonal antibody development for proteins in a proteome Pay for successful antibodies only |
|
A product of Absolution |
AbProfile™: Discover an array of unbiased differences.? Proteome-scale |
|
|
50,000 monoclonal antibodies on an array.100 times more content. Differential profiling thousands of cell surface receptorsand plasma proteins |
|
A product of Absolution |
|
SMAL™:?All big things have a SMAL beginning. |
|
|
High success rate for mAb generation Deliver a panel of high affinity mAbs Flexible and optional fee structure for minimizing risks |
|
A product of Absolution |
AbX™: X=anything.? Find your antibody within |
|
|
currently 7species.?200,000 mAbs.70,000 proteins 3 new organisms are being AbXed/day Pre-made anti-peptide mAbs against all proteins in nature. |
|
A product of AbStore |
AbStop™: The last stop of antibody development. The most successful stop. |
|
|
Pre-designed antibody packages against high value targets The most aggressive and comprehensive protein targeting Best for diagnostics and therapeutic antibody development |
|
A product of AbStore |