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  • Feature MyBPC (C10-mutation) expression is sufficient to cause contractile dysfunction.
    Application WB
    Species Homo sapiens
    Targets Myosin binding protein C-mutant
    Catergory ATPase activator
    Title A hypertrophic cardiomyopathy-associated MYBPC3 mutation common in populations of South Asian descent causes contractile dysfunction
    Publication Kuster DW, J Biol Chem, 2015
    Methods Western blot analysis using C10 domain-specific polyclonal antibody and C10mut-specific custom monoclonal antibody (clone ID: 8560-1-4M-4K14-1_120915, AbMART, Arlington, MA).