| Feature | Hh-Gli2 signaling markedly increases Igf2 mRNA and activates the Igf-mTORC2-Akt signaling cascade. |
| Application | WB |
| Species | Mus musculus |
| Targets | Gli2 |
| Catergory | Transcription related |
| Title | Hedgehog signaling activates a positive feedback mechanism involving insulin-like growth factors to induce osteoblast differentiation |
| Publication | Shi Y, Proc Natl Acad Sci, 2015 |
| Methods | A monoclonal antibody specific for full-length Gli2 was generated against a peptide within the C-terminal half of mouse Gli2 according to proprietary techniques (Abmart). |
| Figures |
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| Highlights |
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