• Home > Publications
  • Feature Cdk5-mediated phosphorylation of CHIP negatively regulates its neuroprotective function, thereby contributing to neuronal cell death progression following neurotoxic stimuli.
    Application WB
    Species Mus musculus
    Targets CHIP
    Catergory E3 ubiquitin ligase
    Title Phosphorylation of CHIP at Ser20 by Cdk5 promotes tAIF-mediated neuronal death
    Publication Kim C, Cell Death Differ, 2015
    Methods The production of anti-Ser20 CHIP phospho-specific rabbit polyclonal antibody was designed in our laboratory and generated by Abmart (Shanghai, China) using peptide C-TGGGG(pS)PDKSP surrounding the serine 20 residue on mouse CHIP. ...