| Feature | Cdk5-mediated phosphorylation of CHIP negatively regulates its neuroprotective function, thereby contributing to neuronal cell death progression following neurotoxic stimuli. |
| Application | WB |
| Species | Mus musculus |
| Targets | CHIP |
| Catergory | E3 ubiquitin ligase |
| Title | Phosphorylation of CHIP at Ser20 by Cdk5 promotes tAIF-mediated neuronal death |
| Publication | Kim C, Cell Death Differ, 2015 |
| Methods | The production of anti-Ser20 CHIP phospho-specific rabbit polyclonal antibody was designed in our laboratory and generated by Abmart (Shanghai, China) using peptide C-TGGGG(pS)PDKSP surrounding the serine 20 residue on mouse CHIP. ... |
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