Features

 

For a selected proteome, the expressed total protein number can be anywhere between a few hundreds to more than 10,000. Mabome™ offers flexible custom antibody generation for a proteome:

	dependent upon the complexity and the size of a proteome, the protein sample is processed into different fractions
	fraction methods by size, by protein biophysical properties, by are used
	the sample is processed to eliminate known abundant proteins
	fractioned protein antigens are made into potent immunogens
	a large-scale immunization, fusion and antibody selection process is employed
	tens of thousands hybridomas are selected based on their stability, antibody-producing ability and reactivity toward immunogens
	the library is subjected to quality checking by antibody gene sequencing, antibody application validation and antibody cellular target identification