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Similar to the library approach of SEAL™, SMAL™ starts with a combinatorial chemical antigen library (CCAL) design based on the specific structural features of a target chemical molecule
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CCAL typically consists of multiple chemical modifications of the target molecule so that different immunogenic and unique chemical groups are guaranteed to be exposed for generating antibodies |
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Thus produced CCAL is then going through the potent immunogen generation technology (VLP) developed at Abmart for high affinity and specific monoclonal antibody generation |
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SMAL™ has proven to be effective for antibody development against diverse chemicals, thus providing key building blocks (antibodies) for building immunoassay-based detection of important small molecules |